Utilizing peptides against cancer has been long established.1-4 It is fortunate that even with the plethora of cancers needing treatment, there are also nearly innumerable peptides that can be applied to promising therapies. New England Peptide | Peptides International has always carried a large portfolio of these, with literally hundreds available. We will run through just a few of these by categories or individual products, along with some references of associated applications that were recently published.
Antipain Agent Shrinks Oral Cancers, Sparing Healthy Tissue5
Caspase-1-Dependent Inflammasomes Mediate Photoreceptor Cell Death in Photo-Oxidative Damage-Induced Retinal Degeneration6
Structural and Kinetic Evidence of Aging After Organophosphate Inhibition of Human Cathepsin A7
Chlorotoxin Redirects Chimeric Antigen Receptor T Cells for Specific and Effective Targeting of Glioblastoma8
Single-Cell Chromatin profiling Reveals Demethylation-Dependent Metabolic Vulnerabilities of Breast Cancer Epigenome9
High Clusterin (CLU) mRNA Expression Levels in Tumors of Colorectal Cancer Patients Predict a Poor Prognostic Outcome10
A Size‐Changeable Collagenase‐Modified Nanoscavenger for Increasing Penetration and Retention of Nanomedicine in Deep Tumor Tissue11
Fibronectin in the Tumor Microenvironment Activates a TLR4-dependent Inflammatory Response in Lung Cancer Cells12
Monitoring Protease Activity in Biological Tissues Using Antibody Prodrugs as Sensing Probes13
Novel Gastrin-Releasing Peptide Receptor Targeted Near-Infrared Fluorescence Dye for Image-Guided Surgery of Prostate Cancer14
Imaging the Distribution of Gastrin Releasing Peptide Receptors in Cancer15
A Step Forward in Identifying the Right Human Chorionic Gonadotropin Assay for Testicular Cancer16
Abstract P2-12-11: Does Goserelin Have an Effect on Quality of Life in Women Who Have Chemotherapy for Early Breast Cancer? Results from the OPTION Randomised Trial17
Iron and Hepcidin Mediate Human Colorectal Cancer Cell Growth18
Proteolytic Processing of PD-L1 by ADAM Proteases in Breast Cancer Cells19
Design of Fluorogenic Probes and Fluorescent‐Tagged Inhibitors for γ‐Glutamyl Cyclotransferase20
Expression of Melanocortin 1 Receptor Before and After Narrowband UVB Phototherapy Treatment in Patients with Stable Vitiligo: A Prospective Study21
MicroRNA-429 Inhibits Bone Metastasis in Breast Cancer by Regulating CrkL and MMP-922
Nesfatin‑1 is a Potential Diagnostic Biomarker for Gastric Cancer23
Neuropeptide Bombesin Receptor Activation Stimulates Growth of Lung Cancer Cells Through HER3 With a MAPK-Dependent Mechanism24
A Cinical Audit of Use of Octreotide in the Management of Inoperable Malignant Bowel Obstruction at a Large Cancer Centre25
Protease-Activated Receptor Signalling Initiates α5β1-Integrin-Mediated Adhesion in Non-Haematopoietic Cells26
Autophagy Promotes Immune Evasion of Pancreatic Cancer by Degrading MHC-I 27
Mammalian Target of Rapamycin (mTOR) Inhibitors and Skin Cancer Risk in Nonrenal Solid Organ Transplant Recipients: Systematic Review and Meta‐Analysis28
RAS-Like Estrogen-Regulated Growth Inhibitor
miR‑532‑5p Promotes Breast Cancer Proliferation and Migration by Targeting RERG29
Targeting Integrins with Radiolabeled RGD Analogs for Radiotheranostics of Metastatic Radioactive Iodine Non-Responsive Thyroid Cancer–New Avenues in…30
Sirtuin 3 Induces Apoptosis and Necroptosis by Regulating Mutant p53 Expression in Small‑Cell Lung Cancer31
Expression of Somatostatin Receptors Subtypes (1-5) mRNA in MCF7 and MDA-MB231 Breast Cancer Human Cell Lines32 (in review)
Chimera RNA Interference Knockdown of γ-Synuclein in Human Cortical Astrocytes Results in Mitotic Catastrophe33
Cyclosporin A Activates Human Hepatocellular Carcinoma (HepG2 cells) Proliferation: Implication of EGFR-Mediated ERK1/2 Signaling Pathway34
Control of Cancer Progression by Extracorporeal Removal of Soluble TNF-alpha Receptors35
Basic Fibroblast Growth Factor Blockade Enhances Lung Cancer Cell Invasion by Activating the AKT/MMP‐2/VEGF Pathway36
ME Kit for Exosome Isolation
Need to isolate exosomes for your research? Use the ME™ Kit!
• Specific isolation of extracellular vesicles (exosomes, microvesicles) in as little as 45 minutes.
• No ultracentrifugation required!
• Works for multiple sample types (plasma, urine, culture media, etc.) across several species.
• Can be modified to fit specific needs (multiple chemistries, added to beads, etc.).
• Comes complete with positive and negative controls.
• Extracellular vesicle (EV) isolation for functional studies
• RNA isolation
• DNA isolation
• Protein isolation
• miRNA isolation
Custom Peptide Synthesis
At NEP | PI, we specialize in meeting our customer’s needs and delivering the highest purity in the industry. Hallmarks of our custom peptide synthesis services include:
- Peptides: simple to complex peptide synthesis.
- Scale: from mg to kg scales.
- Tools: resins, pre-loaded resins, and protected amino acid derivatives.
Our experienced scientists will work with you to personally ensure that your compound meets your specification. Whether the issue is purity, quantity, or time, we will see to it that you are satisfied. You have our word on it.
Should you be interested in these, or any other cancer research peptides or proteins, please feel free to contact us. Of course, we can always tailor a custom peptide synthesis project combining these items, or a completely unique item to your specifications.
- doi: https://doi.org/10.1101/2020.01.24.918888
- doi: 10.7150/jca.39771
- doi: 10.1515/cclm-2019-0319
- doi: 10.1200/JCO.2020.38.5